Popular Burnley town centre pub on market
The Brun Lea on Manchester Road is one of 16 pubs that has been put up for sale by pub giant J D Wetherspoon.
A spokesman for Wetherspoons said: "We understand that our loyal customers and staff will be disappointed with this decision.
"However JDW does occasionally put pubs up for sale.
"This is a commercial decision taken by the company after long consideration."
The spokesman added that trade would continue as normal until a buyer was found.
He also gave an assurance that if the existing 39 staff at the Brun Lea were not taken on by the new owners Wetherspoons would try to find them work at other outlets across the region.
The Boot in Burnley is also part of the pub chain.
A regular customer said: "It is disappointing news because this is a popular boozer with a great selection of beers and it is cheap."