Scott Parker’s men will be out to extend their long, impressive unbeaten run, which now stands at 21 games in league and cup – following their midweek 2-0 win against Hull City.
They face a PNE side that also picked up an impressive result on Tuesday night, going away to Carrow Road and beating Norwich City 1-0.
On the injury front, the Clarets are coming close to boasting a fully fit squad, although the likes of Enock Agyei and Nathan Redmond – who have recently returned from injury – are still not quite up to speed.
Both sides have some injury concerns to contend with heading into Saturday’s encounter, so here's an early look at the team news for both outfits:
9. Luca Koleosho (Burnley) - doubt
Faces a race against time to be fit after missing Burnley’s last four games with a knock he picked up in training before the trip to Portsmouth. Photo: Matt McNulty
10. Aaron Ramsey (Burnley) - out
Making good progress in his recovery from a serious knee injury, which he suffered back in February of last year. But not quite ready just yet. Photo: Matt McNulty
11. Mike Tresor (Burnley) - out
Despite making a recent return during the FA Cup tie against Reading, it’s understood Tresor is not fit to play and is unlikely to be available for the foreseeable future. Photo: Lewis Storey
12. Ali McCann (Preston) - suspended
McCann serves the second game of his two-match ban after being shown his 10th yellow card of the season during the recent game against Blackburn. Photo: Ben Roberts Photo