Unbeaten in 17 games in league and cup, Scott Parker’s men will be desperate to build on Monday night’s 0-0 draw with leaders Leeds with a victory.
The Clarets currently sit third in the table, just a point off Sheffield United.
As for Pompey, they remain 21st and just two points above the dropzone following their midweek 1-0 defeat to Millwall.
Burnley are unlikely to have any of their injured players back for this one, but they will have one or two waiting in the wings pushing to start.
With that in mind, here’s how we think the Clarets might line up:
9. RW - Jaidon Anthony
Anthony is the one winger that is virtually guaranteed to start every game. Puts in a huge shift and brings an attacking threat. Photo: Matt McNulty
10. LW - Hannibal
It didn't quite work out for Lyle Foster against Leeds, so is it time to revisit Hannibal on the left wing again? He showed some promising signs there before his recent ban. Photo: Molly Darlington
11. ST - Zian Flemming
With five goals in his last four away games, Flemming will be desperate to continue his impressive scoring run on the road. Photo: Matt McNulty