Scott Parker’s side rose to the summit on Saturday for the first time in 169 days thanks to their hard-fought 2-1 win against Coventry City.
The victory saw them leapfrog Sheffield United and Leeds United, who both failed to claim three points.
The Clarets are likely to be without Manuel Benson for tonight’s clash after the winger was absent at the weekend as a result of an ankle problem he sustained in training.
Aaron Ramsey and Mike Tresor are both likely to remain out despite their recent returns for the Under-21s, while Jordan Beyer, Bashir Humphreys, Jonjo Shelvey and Enock Agyei are all sidelined.
With that in mind, here’s how we think the Clarets will line up at Pride Park:
5. LB - Lucas Pires
The Brazilian continued his fine form with another impressive display at Coventry, even if he could have done better for the early goal. Photo: Alex Livesey
6. CM - Josh Cullen
Cullen quietly went about his midfield at Coventry on Saturday amid the madness all around him. Understated but never under-appreciated. Photo: Matthew Lewis
7. CM - Josh Laurent
Hannibal is an option if Scott Parker wishes to rotate, but Laurent's physicality and energy could prove key against a combative Derby side. Photo: Alex Livesey
8. CAM - Josh Brownhill
Can Burnley's top goalscorer bag his 14th of the season? Don't bet against him. Photo: Matthew Lewis