Both sides head into the game in desperate need of a win, as the relegation battle continues to intensify now the season is past the midway stage.
The last time the two sides faced each other, back in 2020, the Clarets secured a 1-0 win at Turf Moor, thanks to Jay Rodriguez's second-half goal.
While Burnley didn't have the most memorable of January transfer windows, they did at least manage to find a replacement for Chris Wood, bringing in Netherlands international Wout Weghorst.
Discussing the new signing, Clarets boss Sean Dyche said: “Wout is a player that our scouts have been strong on for some time and we feel that he can add to all that we do at Burnley Football Club.
His signing is a continued show of the Club’s and team’s development. We wish Wout well as he earns the right to push our group forwards.”
Chairman Alan Pace added: “I’d like to wish Wout a very warm welcome to Burnley Football Club.
“We’re absolutely delighted to have brought in a great talent with a fantastic goal-scoring pedigree in Germany. I look forward to him joining up with Sean and the team.
“January is a famously difficult window, as we all know. I am however delighted that a lot of hard work by everyone involved has paid off.”
Take a look at all the latest stories from the Premier League, as the reaction to Monday's enthralling transfer deadline day continues:
9. van Basten takes pop at Burnley
Ex-Netherlands star Marco van Basten has revealed his shock at Burnley signing striker Wout Weghorst from VfL Wolfsburg. He's claimed the Clarets are "going to be relegated" and also criticised the player's ball retention ability. (Sport Witness) Photo: Stuart Franklin
10. Hammers miss out on Zapata
West Ham United are believed to have missed out on a late deadline day swoop for Atalanta striker Duvan Zapata. The Hammers were said to have made a late loan offer for the Colombia international, but failed to get the deal over the line. (Sky Sports News) Photo: MARCO BERTORELLO