Scott Parker’s side stretched their unbeaten run to 20 games in league and cup following their 1-0 win against Southampton in the FA Cup at the weekend.
While they were in cup action, Sunderland were held to a draw by Watford while Sheffield United beat Portsmouth to reclaim second place, demoting the Clarets back down to third.
The Clarets face a Hull side that hover just one point above the relegation zone, but did pick up a surprise 3-0 win against the Blades at the end of January.
Burnley have the likes of Enock Agyei, Manuel Benson and Nathan Redmond back from injury, although as we know Parker likes to play it cautious with returning players and is unlikely to risk them from the start.
Both sides have some injury concerns to contend with heading into Wednesday night’s encounter, so here's an early look at the team news for both outfits:
5. Mike Tresor (Burnley) - out
Despite making a recent return during the FA Cup tie against Reading, it’s understood Tresor is not fit to play and is unlikely to be available for the foreseeable future. Photo: Lewis Storey
6. Mohamed Belloumi (Hull) - out
The Tigers confirmed in November the winger had suffered an ACL injury and is facing an extended spell on the sidelines. Photo: Cameron Howard
7. Charlie Hughes (Hull) - out
The highly-rated defender hasn’t featured since picking up a hamstring injury just before Christmas. Photo: George Wood
8. Liam Millar (Hull) - out
The winger has also been out since suffering an ACL knee injury during the initial fixture against Burnley back in October. Photo: George Wood