Even without a depleted squad, the Clarets boss would have rested the vast majority of his starting XI – as we’ve witnessed in cup competitions throughout his tenure.
But with eight players missing out against Manchester United in midweek and the squad still stretched, he’ll certainly use this occasion to hand minutes to fringe players and perhaps even the odd youngster or two.
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Parker is boosted by the return of the three AFCON players, Axel Tuanzebe, Hannibal and Lyle Foster, while Maxime Esteve also returned from injury in midweek.
But with Premier League survival clearly the priority, how many changes can we expect to see?
Here’s how we expect Burnley to line up:
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5. LB - Quilindschy Hartman
After returning to Burnley's bench in midweek, this seems like the perfect chance to get Hartman back in the team (Photo by Molly Darlington/Getty Images) Photo: Molly Darlington
6. CM - Josh Laurent
He could do with a rest, but Burnley are short on options in midfield with Josh Cullen out injured (Photo by Michael Regan/Getty Images) Photo: Michael Regan
7. CM - Hannibal
Hannibal is another one that could do with a rest given he's just returned from AFCON, but Burnley don't have that luxury at the moment (Photo by Mike Hewitt/Getty Images) Photo: Mike Hewitt
8. RW - Loum Tchaouna
Tchaouna needs to grab this chance if he's going to feature more prominently in the league going forwards (Photo by Steve Bardens/Getty Images) Photo: Steve Bardens