Vincent Kompany’s men will be out to build on their morale boosting 2-1 win against Brentford prior to the break.
Coupled with Nottingham Forest’s points deduction, it saw the gap to safety reduce to just five points – giving the Clarets plenty to play for during the final nine games of the campaign.
They will be without the ineligible David Fofana at Stamford Bridge, while Ameen Al-Dakhil, Jordan Beyer, Han-Noah Massengo, Aaron Ramsey, Luca Koleosho and Nathan Redmond are all likely to remain sidelined.
With that in mind, here’s how we think the Clarets could line up: