Vincent Kompany has confirmed Manuel Benson is struggling with a “niggle”, having not featured in pre-season, while Josh Cullen is also a doubt.
Darko Churlinov (health scare) and Michael Obafemi (hamstring) are also expected to be absent.
In total there are new players who could make their Burnley debut, including goalkeeper James Trafford who made the switch from Man City earlier this summer.
With all that in mind, here’s how the Clarets could line up this evening...
1. Decisions to make
HUELVA, SPAIN - JULY 28: Vincent Kompany, manager of Burnley speaks with Connor Roberts of Burnley FC during a Pre Season Friendly Match between Real Betis and Burnley FC at Estadio Nuevo Colombino on July 28, 2023 in Huelva, Spain. (Photo by Fran Santiago/Getty Images) Photo: Fran Santiago
2. GK - James Trafford
Deciding who to start in goal is probably the biggest decision Kompany has to make, with Arijanet Muric also a strong contender. Photo: Fran Santiago
3. RB - Connor Roberts
Featured regularly in pre-season and will be hoping to build on his impressive campaign last time out. Photo: Fran Santiago
4. CB - Jordan Beyer
This is another position where Vincent Kompany has plenty of options to choose from, with each player as strong as the other. Photo: Fran Santiago