Clarets skipper left out of England squad
Heaton had been named in the last four squads by coach Roy Hodgson, without making his debut, and was also selected for a get-together at St George's Park last month.
However, Hodgson has opted to recall Southampton keeper Fraser Forster, who has kept six clean sheets I'm 10 games since returning from a broken kneecap, suffered against the Clarets at St Mary's a year ago.
Leicester City midfielder Danny Drinkwater has been handed his first England call-up, while Liverpool striker Daniel Sturridge has returned to the squad after returning to injury.
Goalkeepers: Butland, Forster, Hart.
Defenders: Bertrand, Cahill, Clyne, Jagielka, Rose, Smalling, Stones, Walker.
Midfielders: Alli, Barkley, Dier, Drinkwater, Henderson, Lallana, Milner, Sterling.
Forwards: Kane, Sturridge, Vardy, Walcott, Welbeck.