Scott Parker’s men will be determined to issue a reaction after being knocked out of the cup at the fifth round stage with a 3-0 defeat to Preston North End.
While they were in cup action, Sheffield United beat QPR to extend their lead to Burnley in third back to five points.
With 12 games remaining, the Clarets now have one sole focus as they go all out for automatic promotion.
Still unbeaten in their last 21 league games, and yet to concede in 12 straight outings, Burnley will need to continue that form with a much-needed three points in the Welsh capital.
Both sides have some injury concerns to contend with heading into Tuesday night’s encounter, so here's an early look at the team news for both outfits:
5. Ollie Tanner (Cardiff) - out
The winger has picked up a knee injury that is expected to keep him out for a few weeks. Photo: Ryan Hiscott
6. David Turnbull (Cardiff) - out
The midfielder could return to action this month following a recovery from a hamstring injury, which required surgery. But this game is likely to come too soon. Photo: George Wood
7. Jordan Beyer (Burnley) - out
The defender remains a long-term absentee despite recently returning to training following a second operation on his meniscus (knee) injury, which has kept him out of action since December 2023. Photo: Ryan Pierse
8. Bashir Humphreys (Burnley) - out
The loanee is facing “some time” on the sidelines after picking up a quad injury prior to the recent game against Sheffield Wednesday. Photo: Alex Livesey