The Ivory Coast International, who has five goals in eight Premier League starts, pulled up in the first half just before Newcastle United had got their noses in front.
The Clarets' leading scorer is believed to have sustained a thigh strain when attempting to play a pass to team-mate Chris Wood, and marched straight down the tunnel when replaced by Matej Vydra.
"He's a threat and he offers us something different in the way that he plays, with his movement patterns and he sees things slightly differently," said Dyche. "I thought he had looked sharp so he was a loss at that time.
"It came when he was trying to thread Woody through, they had started the game together very well, so that was a loss for us today. He offers us something different in that position, which he's growing in to.
"He was sharp and he looked alive and gave us something different in the first half. I think it is a thigh strain so we will wait and see how that calms down."
"He's a threat and he offers us something different in the way that he plays, with his movement patterns and he sees things slightly differently," said Dyche. "I thought he had looked sharp so he was a loss at that time.
5. Toon given Sule chance
Bayern Munich CEO Oliver Kahn has opened the door to Newcastle United while admitting that Bundesliga winner Niklas Sule could leave the Allianz Arena. (Mia San Mia) (Photo by Alexander Hassenstein/Getty Images)
Photo: Alexander Hassenstein
6. Leeds prepare Mariano offer
Leeds United are readying an offer to secure the signing of Mariano Diaz from Real Madrid in the January transfer window. (El Nacional) (Photo by Angel Martinez/Getty Images)
Photo: Angel Martinez
7. Botman on Magpies radar
Newcastle United are reportedly considering a move for Lille centre-back Sven Botman. (The Athletic) (Photo by Christian Kaspar-Bartke/Getty Images)
Photo: Christian Kaspar-Bartke
8. Lawrence in demand
Watford, West Bromwich Albion, Norwich City and Burnley are keen on signing Tom Lawrence from Derby County. (Football League World) (Photo by Marc Atkins/Getty Images)
Photo: Marc Atkins