Burnley were well beaten by Nelson at MyProtein Turf Moor on Friday night in their latest Lancashire League 20/20 outing.
Nelson professional Ryan Canning (50) and Tyler McGladdery (73) put on 130 for the first wicket, to set the visitors well on the way to a third win from three games, to take them top of Group C by four points from holders Lowerhouse, who have played a game less.
Russ Bradley also hit an unbeaten 23 as the Seedhill side closed on 156-3.
In reply, Burnley were legged back by eight Nelson bowlers as they were restricted to 133-8.
Things started badly as Dan Pickup was snapped up on the boundary by Sam Halstead off visiting captain Neil Thompson for a duck off only the second ball.
But professional Chris Holt (35) and skipper Bharat Tripathi (32) set about a recovery, as they shared 67 for the second wicket.
However, 67-2 became 78-4, and despite contributions from Aiden Tate (15), Chris Burton (13) and Cole Hayman (12), Burnley finished short, and remain with one victory after three games.
Burnley have no game on Friday night, but Lowerhouse return to action as they look to defend their title, entertaining Todmorden at the Neville Gee Recruitment Ground.
Nelson face Colne at Seedhill in the other game in Group C.
Next Friday, July 4th, sees the final group fixtures as Colne host Lowerhouse at the Horsfield and Burnley travel to Todmorden.
The three group winners and best runner-up progress to the semi-finals on July 11th.