Junction 8 of the westbound carriageway on the M65 has been closed following a multi-vehicle accident, say police.
The accident which happened shortly after 7.30am at junction 7 for Dunkenhalgh Way is thought to involve a lorry, say police.
One person was reported to have been trapped in their vehicle.
The eastbound carriageway was closed to allow the air ambulance to land.
A spokesman for the police said: "We are closing junction 8 on the M65 westbound carriageway to stop vehicles joining and getting stuck in traffic and so we can deal with the accident at junction 7."