Padiham ended up on the wrong side of an eight-goal thriller at the Arbories on Wednesday night.
Accrington Stanley loanee James Jenkins put the Storks ahead after only three minutes, and Ben Deegan headed Droylsden level a minute later.
Padiham then had an effort cleared off the visitors goal line on five minutes and at the other end Dale Wright headed against the outside of the post a minute later.
The game continued to be played at a fast pace and on 20 minutes Padiham regained the lead after a mazy run by Dominic Craig led to new signing Curtis Haley curling his shot past keeper Russ Saunders.
However, again the Storks couldnt hang onto their advantage and within a minute Droylsden were level once more, as Ali Brown scored from close range.
Padiham had a great chance to go in front for a third time in the run up to the break when Jenkins was clean through on goal, but blasted his shot wide.
And deep into first half stoppage time Adam Mornings header could only be pushed into his own goal by Storks keeper Ross Dawson to leave Droylsden 3-2 ahead at half-time.
Droylsden increased their lead on 56 minutes after Fernando Moke engineered space on the edge of the Padiham 18-yard-box before chipping Dawson.
Louis Mayers reduced the visitors’ lead to a single goal on 61 minutes after closing down Saunders and defender Dan Caldercott.
But on 65 minutes Deegan secured the points for the visitors with a headed goal that made it 5-3, and took Droylsden’s goalscoring record to 21 goals in six league outings this season.
Padiham travel to New Mills on Saturday in a rearranged fixture, while Padiham Reserves are at home to Curzon Ashton in the Galaxy Lancashire Football League, kick-off 3 p.m.
Away from football, the Storks’ management committee and supporters were shocked to hear the news that long-standing club treasurer Keith Large had passed away during the game while in hospital in Blackburn.
Club secretary Alan Smith said: “Our thoughts go out to Keiths family and friends at this sad time, and as an organisation we are going to miss his input into the running of Padiham Football Club, of which he has been a long standing member and friend.”