Clarets striker Sam Vokes has suffered a big injury blow after limping out of Saturday’s 2-0 defeat to Leicester City.
The Welsh international has been diagnosed with a rupture of the anterior cruciate ligament in his left knee.
The forward, who has scored 20 Championship goals, picked up the injury after just five minutes of the top-of-the-table clash with league leaders Leicester at Turf Moor.
Scans revealed the extent of the injury and Vokes will now be seeking specialist advice this week.
The injury is the latest blow to boss Sean Dyche and his promotion-chasing Clarets side.
However, top scorer Danny Ings is making good progress in his recovery from an ankle injury and is expected to rejoin the squad soon.
Burnley manager Sean Dyche said: “Sam has had a great season and I am sure you will join us all in supporting him during his recovery.
“As ever, our team mentality remains focused and this represents another opportunity for someone to come and make a continued contribution in the closing weeks of the season.”